I guess it does not really count as cancelled as the creator had, according to The Hollywood Reporter, long planned on ending it's run during the 2021-2022 TV season.
The show, which got the country both talking, and crying every week, has been on for six seasons. As the Hollywood Reporter writes, show creator Dan Fogelman said after season three that the show was at it's "midpoint".
This Is Us stars Milo Ventimiglia, Sterling K. Brown, Christy Metz, and of course, one of my favorites, Mandy Moore (who remembers Chasing Liberty or when she played herself on several episodes of Entourage).
Ok, sorry...I had to put this up!