Kelsey Grammer holds the record for playing the same character longer than any other actor (or character). The role of Fraiser Crane was originally just slated to be on a few episodes of an early season of the NBC sitcom CHEERS. When the show Fraiser ended in 2004 after 11 seasons, Grammer had been playing the character for 20 years! The show, by the way, won 37 Emmy Awards
And now...he's BACK! He recently said "I gleefully anticipate sharing the next chapter in the continuing journey of Dr. Frasier Crane."
As of now, none of the other series regulars have officially signed on to the new show which will stream on the new Paramount Plus (which is currently CBS All Access until later this week when it morphs into Paramount Plus).